ea0073aep839 | Late Breaking | ECE2021
Coopmans Eva
, Korpershoek Esther
, M.F. van Velthuysen
, Adrian F. Daly
, Beckers Albert
, Aart Jan Van der Lely
, Neggers Sebastian
, Hofland Hans
, Feelders Richard
, Wouter W de Herder
ContextGermline mutations in the aryl hydrocarbon receptor-interacting protein (AIP) have been identified in patients with pituitary adenomas, most frequently presenting as somatotropinomas in the setting of familial isolated pituitary adenoma (FIPA). Our current understanding of AIP related tumorigenesis indicates that it leads to isolated pituitary adenomans, while other associated tumors have not typically been considered part of the...